Alaabta
Lifecosm CHW Ag/Anaplasma Ab/E.canis Ab Qalabka Tijaabada Daawooyinka Xoolaha
Kanine Heartworm Ag/ Anaplasma Ab /Ehrlichia canis Qalabka tijaabada ah
| Lambarka buugaagta | RC-CF29 |
| Soo koobid | Ogaanshaha Canine Dirofilaria immitis antigens, Antibodies Anaplasma, E. canis antibodies 10 daqiiqo gudahood |
| Mabda'a | Hal tallaabo oo tijaabo ah oo immunochromatographic ah |
| Bartilmaameedyada ogaanshaha | CHW Ag : Dirofilaria immitis antigens Anapalsma Ab : unugyada difaaca jirka AnaplasmaE. canis Ab : E. canis antibodies |
| Tusaale | Dhiiga Dhan ee Canine, Plasma ama Serum |
| Waqtiga akhriska | 10 daqiiqo |
| Tirada | 1 sanduuq (xirmo) = 10 qalab (xirmo shaqsiyeed) |
| Nuxurka | Qalabka tijaabada, dhalada kaydka ah, iyo dhibicda la tuuri karo |
| Kaydinta | Heerkulka qolka (waqtiga 2 ~ 30 ℃) |
| Dhicis | 24 bilood ka dib wax soo saarka |
| Digniin | Isticmaal 10 daqiiqo gudahood ka dib furitaankaIsticmaal qadar ku habboon oo muunad ah (0.01 ml oo dhibco ah) Isticmaal 15 ~ 30 daqiiqo ka dib RT haddii ay ku kaydsan yihiin xaalado qabow Tixgeli natiijada imtixaanku inay khaldan yihiin 10 daqiiqo ka dib |
Xog
Gooryaanka wadnaha ee qaangaarka ah waxay koraan dhowr inji oo dherer ah waxayna degan yihiin halbowlayaasha sambabada halkaasoo ay ka heli karaan nafaqooyin ku filan.Gooryaanka wadnaha ee gudaha halbowlayaasha ayaa keena barar waxayna sameeyaan hematoma.Wadnaha, markaa, waa in uu si ka badan sidii hore u soo shubaa marka gooryaanka wadnuhu uu kordho tirada, oo xannibaya halbowlayaasha.
Marka infekshanku xumaado (in ka badan 25 wadneworms ayaa ku jira eey 18kg ah), gooryaanka wadnuhu waxay u dhaqaaqaan atrium midig, iyagoo xannibaya socodka dhiigga.
Marka tirada gooryaanka wadnaha ay gaaraan in ka badan 50, way qabsan karaan
atrium iyo ventricles.
Marka uu cudurku ku dhaco in ka badan 100 gooryaan wadnaha ah oo ku yaal qaybta saxda ah ee wadnaha, eygu wuxuu lumiyaa shaqada wadnaha oo ugu dambeyntii dhinto.Tani dilaa ah
ifafaale waxa loo yaqaan "Caval Syndrom."
Si ka duwan dulinnada kale, gooryaanka wadnuhu waxay jiifiyaan cayayaan yaryar oo loo yaqaan microfilaria.Microfilaria ee kaneecada waxay u guurtaa ey marka kaneecadu ay dhiiga ka nuugo eeyga.Gooryaanka wadnaha ee ku noolaan kara guriga 2 sano ayaa dhimanaya haddii aysan u guurin marti kale muddadaas.Dulin-ku-nooleyaasha ku nool eeyga uurka leh waxay ku dhici karaan embriyaha.
Baaritaanka hore ee gooryaanka wadnaha ayaa aad muhiim u ah baabi'inta iyaga.Gooryaanka wadnaha waxa uu maraa dhawr tillaabo sida L1, L2, L3 oo ay ku jiraan heerka gudbinta ee kaneecada si ay u noqdaan gooryaanka wadnaha ee qaangaarka ah.
Gooryaanka wadnaha ee kaneecada
Microfilaria ee kaneecada waxay u koraan L2 iyo L3 dulin awood u leh inay eeyaha qaadsiiso dhowr toddobaad gudahood.Koritaanku wuxuu ku xiran yahay cimilada.Heerkulka ugu wanaagsan dulinku wuxuu ka sarreeyaa 13.9 ℃.
Marka kaneecada cudurka qabta ay ey qaniinto, microfilaria ee L3 ayaa gudaha u gasha maqaarka.Maqaarka, microfilaria waxay u koraan L4 1 ~ 2 toddobaad.Ka dib markii uu ku noolaado maqaarka muddo 3 bilood ah, L4 wuxuu u baxaa L5, kaas oo u dhaqaaqa dhiig.
L5 sida qaabka wadnaha ee qaangaarka ah ayaa gala wadnaha iyo halbowlayaasha sambabada halkaas oo 5 ~ 7 bilood ka dib gooryaanka wadnaha ay jiifaan cayayaanka.
Daawaynta
Infekshanka gooryaanka wadnaha ayaa si guul leh loo daaweeyaa xaaladaha intooda badan.Si loo baabi'iyo dhammaan gooryaanka wadnaha, isticmaalka dawooyinka ayaa ah habka ugu wanaagsan.Ogaanshaha hore ee gooryaanka wadnaha ayaa kor u qaada heerka guusha ee daaweynta.Si kastaba ha noqotee, marxaladda dambe ee caabuqa, dhibaatooyin ayaa dhici kara, taasoo ka dhigaysa daaweynta mid aad u adag.
Xog
Bakteeriyada Anaplasma phagocytophilum (oo hore u ahaan jirtay Ehrilichia phagocytophila) waxay keeni kartaa infekshan ku dhaca noocyo badan oo xayawaan ah oo uu ku jiro aadanaha.Cudurka ku dhaca ariga guriga waxaa sidoo kale loo yaqaan qandhada shilinta (TBF), waxaana la yaqaanay ugu yaraan 200 oo sano.Bakteeriyada qoyska Anaplasmataceae waa garaam-negative, nonmotile, coccoid ilaa noolaha ellipsoid, oo ku kala duwan cabbirka 0.2 ilaa 2.0um dhexroor.Waxay yihiin aerobes waajib ah, oo aan lahayn dariiqa glycolytic, dhammaantoodna waa dulin ku-meel-gaar ah oo ku-meel-gaar ah.Dhammaan noocyada genus Anaplasma waxay ku nool yihiin vacuoles xuub-ku-saleysan oo ku jira unugyo hematopoietic ah oo aan qaan-gaarin ama qaan-gaar ah ee martida naasleyda.Fagocytofilum wuxuu waxyeeleeyaa neutrophils iyo ereyga granulocytotropic waxaa loola jeedaa neutrophils cudurka qaba.Noolaha dhif ah, ayaa laga helay eosinophils.
Anaplasma phagocytophilum
Astaamaha
Calaamadaha caafimaad ee caadiga ah ee anaplasmosis canine waxaa ka mid ah qandho sare, caajisnimo, niyad-jab iyo polyarthritis.Calaamadaha neerfaha (ataxia, suuxdin iyo qoor xanuun) ayaa sidoo kale la arki karaa.Infekshanka Anaplasma phagocytophilum waa dhif dhimasho ilaa ay ku adkaato caabuqyada kale.Khasaaraha tooska ah, xaaladaha curyaaminta iyo khasaaraha wax soo saarka ayaa lagu arkay baraarka.Ilmo soo rididda iyo shahwada daciifka ah ee idaha iyo lo'da waa la duubay.Darnaanta caabuqa waxaa saameeya dhowr arrimood, sida kala duwanaanshaha Anaplasma phagocytophilum ee ku lug leh, cudur-sidaha kale, da'da, heerka difaaca jirka iyo xaaladda qofka martida loo yahay, iyo arrimo ay ka mid yihiin cimilada iyo maamulka.Waa in la xuso in astaamaha bukaan-socodka ee bini-aadmiga ay u dhexeeyaan jirro fudud oo hargab oo kale ah, iyo caabuq nafta halis gelinaya.Si kastaba ha ahaatee, inta badan infekshannada bini'aadamka waxay u badan tahay inay keenaan wax yar ama aan lahayn muuqaal caafimaad.
Gudbinta
Anaplasma phagocytophilum waxaa lagu kala qaadaa shilinta ixodid.Gudaha Maraykanka faleebooyinka ugu waaweyn waa Ixodes scapularis iyo Ixodes pacificus, halka Ixode ricinus la ogaaday inuu yahay fayraska exophilic ee Yurub.Anaplasma phagocytophilum waxaa si toos ah u gudbiya shilintan vector, mana jirto wax caddaynaya gudbinta transovarial.Inta badan cilmi-baadhisyada ilaa hadda lagu baaray muhiimada ay leeyihiin naasleyda A. phagocytophilum iyo xuubka shilinta ayaa diiradda saaray jiirka laakiin noolahani wuxuu leeyahay naasley ballaaran oo kala duwan, oo uu ku dhaco bisadaha, eyda, idaha, lo'da, iyo fardaha.
ogaanshaha
Immunofluorescence assay ee aan tooska ahayn waa baaritaanka ugu muhiimsan ee loo isticmaalo in lagu ogaado caabuqa.Shaybaarada serum wejiga degdega ah iyo kuwa qallafsan waa la qiimeyn karaa si loo raadiyo isbeddel afar-laab ah ee titer antibody ilaa Anaplasma phagocytophilum.Intracellular inclusions (morulea) ayaa lagu arkay granulocytes ee Wright ama Gimsa smears dhiiga.Hababka silsiladda polymerase (PCR) ayaa loo isticmaalaa si loo ogaado Anaplasma phagocytophilum DNA.
Ka hortagga
Ma jiro wax tallaal ah oo la heli karo si looga hortago caabuqa Anaplasma phagocytofilum.Kahortaggu waxay ku tiirsan tahay ka fogaanshaha soo-gaadhista shilinta (Ixodes scapularis, Ixodes pacificus, iyo Ixode ricinus) laga bilaabo guga ilaa dayrta, isticmaalka kahortaga ee antiacaricides, iyo isticmaalka prophylactic ee doxycycline ama tetracycline markaad booqanayso Ixodes scapularis, Ixodes pacificus, iyo Ixodes pacificus. gobollada cidhiidhiga ah.
Xog
Ehrlichia canis waa dulin yar oo ul qaabaysan oo ay gudbiso saxanka eyga brown, Rhipicephalus sanguineus.E. canis waa sababta ehrlichiosis qadiimiga ah ee eyda.Eeyaha waxaa laga yaabaa inay qaadaan dhowr Ehrlichia spp.laakiin kan ugu badan ee keena canine ehrlichiosis waa E. canis.
E. canis ayaa hadda la ogaaday inuu ku faafay dhammaan Maraykanka, Yurub, Koonfurta Ameerika, Aasiya iyo Mediterranean.
Eeyaha cudurka qaba ee aan la daawayn waxay noqon karaan asymptomatic sidayaal cudurka muddo sanado ah waxayna ugu dambeyntii u dhintaan dhiigbax weyn.
Astaamaha
Infekshanka Ehrlichia canis ee eeyaha waxa loo qaybiyaa 3 marxaladood;
WAJIGA XANUUNKA AH: Kani guud ahaan waa marxalad aad u khafiif ah.Eeygu wuxuu noqon doonaa mid aan tabo lahayn, cunto ka baxsan, waxaana laga yaabaa inuu leeyahay qanjidhada qanjidhada oo weyn.Waxaa laga yaabaa inay qandho leedahay sidoo kale laakiin marar dhif ah marxaladani ma disho eyga.Inta badan noolaha ayaa iskood u nadiifiya laakiin qaar ayaa u gudbi doona wejiga xiga.
WAJIGA SUBCLINICAL: Marxaladdan, eeygu wuxuu u muuqdaa mid caadi ah.Nooluhu waxa uu ku soo wareegay beeryarada oo asal ahaan halkaas ayuu ku dhuumanayaa.
WAJIGA raagta: Marxaladdan eygu mar kale buu bukoodaa.Ilaa 60% eyda uu ku dhacay E. canis waxay yeelan doonaan dhiig-bax aan caadi ahayn taasoo ay ugu wacan tahay tirooyinka platelets oo yaraada.Caabuqa qoto dheer ee indhaha ee loo yaqaan "uveitis" ayaa laga yaabaa inuu ku dhaco natiijada kicinta difaaca ee muddada dheer.Saamaynta neerfaha ayaa sidoo kale laga yaabaa in la arko.
ogaanshaha iyo daaweynta
Ogaanshaha saxda ah ee Ehrlichia canis waxay u baahan tahay muuqaal morula gudaha monocytes on cytology, ogaanshaha E. canis serum antibodies oo leh baaritaanka aan tooska ahayn ee immunofluorescence antibody (IFA), falcelinta silsiladda polymerase (PCR) kor u qaadida, iyo/ama jel blotting (Western immunoblotting).
Waxa ugu muhiimsan ee ka hortagga ehrlichiosis canine waa xakamaynta shilinta.Daawada doorashada ee daaweynta dhammaan noocyada ehrlichiosis waa doxycycline ugu yaraan hal bil.Waa in ay jirto horumar caafimaad oo la taaban karo 24-48 saacadood gudahood ka dib bilawga daawaynta eeyaha qaba xanuunka wejiga ba'an ama khafiifka ah ee dabadheeraada.Inta lagu jiro wakhtigan, tirada platelet-ka waxay bilaabataa inay korodho waana inay caadi noqotaa 14 maalmood gudahood ka dib bilawga daaweynta.
Caabuqa ka dib, waxaa suurtagal ah in dib loo qaado;difaacu ma waaro ka dib infekshan hore.
Ka hortagga
Kahortagga ugu fiican ee ehrlichiosis waa in eeyaha laga ilaaliyo shilinta.Tan waa in ay ku jirtaa in maqaarka laga eego maalin kasta shilinta iyo in eeyaha lagu daaweyo xakamaynta shilinta.Maadaama shilintu ay sido cudurro kale oo waxyeeleeya, sida cudurka Lyme, anaplasmosis iyo Rocky Mountain qandho la arkay, waxaa muhiim ah in eeyaha laga ilaaliyo inay saxan yihiin.
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